Tag: crp

~~Call To Action BioMarkers for the Anti-Inflammation ZONE

Call To Action BioMarkers for the Anti-Inflammation ZONE

 A few blogs back I reported on the C-Reactive Protein ( CRP) bloodtest for a measure of the inflammation in our bodies….


A couple of days ago I started reading Dr. Barry Sears book, Anti-Inflammation Zone.

anti inflammation zone pic

Great book….. I found that there are a number of test that can determine the level of inflammation in our bodies… especially what he calls SILENT INFLAMMATION….

What is SILENT INFLAMMATION???? You might say…..

As the name implies…. It’s inflammation in our bodies that does not (YET) cause us pain.

Dr. Sears says that almost all pain comes from inflammation…. And if we don’t have pain now we WILL soon have it ….. IF we have a measure of inflammation in our bodies….

So…. We need it measured so  we can 1. Detect it 2. Do something about it.

Dr. Sears documents in his book 2 PRIMARY BIOMARKERS and 2 SECONDARY markers.

The primary markers are:

  1. Silent Inflammation Profile (SIP): This is the “gold standard” test for silent inflammation.  There is a long writeup about this in his book, but suffice

    to say…it measures the balance of pro-inflammatory eicosanoids and anti-inflammatory eicosanoids by measuring the key fatty acid building blocks in the bloodstream for eicosanoids.  These are the harmones that ultimately control inflammation. The key measure is the ARACHIDONIC ACID (or AA (bad)) against the Eico-sapentaenoic acid (or EPA(good)). This actual number should be around 1.5 to 3.0. The LOWER number is IDEAL.


  2. FASTING Insulin Levels (FIL):

    This is a measure of the insulin resistance in our bodies.  Dr. Sears says that Insulin Resistance is the underlying cause of obesity and type 2 diabetes and is characterized by excess insulin in the bloodstream.  The IDEAL measure of insulin resistance is 5 with good being 10….


    Dr. Sears says he firmly believes that high levels, say above 3.0 for SIP and above 10 for FIL is a solid predictor of your likelihood of developing cancer, Alzheimer’s, and heart disease.

    Two secondary measures of Silent Inflammation are the ratio of Total Triglycerides (TG) to HDL (or good cholesterol) and the measure of C-Reactive Protein (which we’ve discussed in an earlier blog).


    These two tests are usually covered by insurance and are the tests the doctor will likely run without hesitation….. HOWEVER….. when you ask for the SIP and FIL tests, you’ll likely get some flack from your doctor.  Mainly for two reasons….they are expensive and the insurance will “likely NOT “ pay for them….. soooo

    You’ll have to pay for them yourself….


    But…if you’re serious about your health… you’ll do this…

    Your ratio of TG/HDL should be no more than 2 and the CRP level should be no more than 1… or as Dr. Sears puts it….. IDEAL for both of these tests are LESS THAN 1,

    And GOOD is LESS THAN 2…

So…. A word to the wise…… get these tests run the next time you’re in for your physical….


For example…… you have to stay on top of it with your doctors… Last October I went in for my annual physical…. I had written on a note the tests that I wanted run on my blood…

When I got the results….none of the tests I requested were done…… WHY….. the doctor said he forgot about it…

NO OTHER REASON….. He did say I could come back in for another blood draw and he would do it….however I had just spent 3 hours there and I was frustrated….so I didn’t go back….

Now I have some additional tests to request…. Even though I Might have to pay for them…. I’m getting it done….

Remember….SIP is best…. FIL is second best…. The other two (TG/HDL ration and CRP) or lesser valuable tests…..but

If that’s all you can get….. get it done….

Next we’ll talk about how to eat right to correct any silent inflammation issues.




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Jerry and Diane


Related Posts:

Call To Action – What the CRAP is CRP????

Call To Action – What the CRAP is CRP????

Let’s talk about Inflammation and CRP.

What the CRAP is CRP????


NO….we’re NOT talking about CRAP… we’re talking about

How does knowing what “CRP is” and knowing
OUR “CRP level” help us with our health?

How does it relate to Inflammation?

Well…. To start CRP stands for C-REACTIVE PROTEIN!


Now what does that mean and why should I
be interested??

All good questions…..so why is it that our
CRP level is not checked by our doctor unless we ask?? 

Then…. Like last time I asked… it
STILL wasn’t checked.

I went in for a routine physical last month and
asked specifically to have my CRP level checked
as well as my Vitamin D3 level…. NEITHER was

I called and ask why it wasn’t checked…. The Doctor
said, “It’s not covered by your insurance”.  I had already
told him that I wanted it checked.  I had even written
a note and handed it to the doctor and told him I would
PAY for it myself…. I just wanted to KNOW!!!

I must say,,,,he did say I could come back into his office
so he could get more blood for the test and he would
have it tested….. It had taken 3+ hours for my physical
so I wasn’t going back in ….. probably should have…. But
I was frustrated….

I asked my son-in-law in California who is
insured by Kaiser Insurance and treated by Kaiser
doctors to have his CRP checked……

Know what happened????? The doctor said NO!

Emphatically No….. he gave no reason, no excuse,
just said no, he was not going to check it.

My son-in-law said to the doctor….. DON’T YOU

Well it made no difference…. Still no CRP checkpoint.

Remember yesterday I talked a little about QUALITY
and the fact that “if you can’t measure it, you can’t
manage it”.  We have to have a “STARTING POINT”
measure of key indicators within our bodies in order
to track our health initiatives…. Remember Deming’s

Doctor Joseph Mercola recently wrote an article with
the title:


Getting Tested for CRP May Save Your Life


See the article here:


Mercola says, “According to findings, high levels
of a protein known as CRP (C-reactive protein) have
been found to increase one’s risk of heart disease.
In fact, studies have suggested the higher the CRP
level, the greater the risk.”

The Role of CRP

CRP measures inflammation and is made in the
liver and in cells lining our blood vessels. Levels of
the protein rise with factors that make heart
disease more probable, such as:

  • Obesity (there’s that word again)
  • Smoking
  • Diabetes
  • High cholesterol

Conversely, levels fall when patients lose weight,
stop smoking and get their diabetes and
cholesterol under control.

Notice, losing weight will help get our diabetes and
cholesterol under control…… that’s OUR responsibility,
NOT the responsibility of a PILL!!! (we’ll talk more about
that later).

Mercola says, “C-reactive protein is known to be a
marker for systemic inflammation.

Our CRP levels should measure between ZERO and ONE
or less than 1.0 (crp<1.0)

So if you’re feeling achy all the time and having lots
of aches and pains…. Be sure to get that CRP level
checked…. That MAY NOT be the total reason for
your issues,,,,but by measuring it and finding it
to be less than one will give you assurance that you
can manage it….or move to the next step in Wellness

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Jerry and Diane




Additional resources:

+Mayo Clinic and C-Reactive Protein Test Results

+ NBC urges women > 40 to test CRP levels

+A Simple Blood Test That Can Save Your Life (Oprah.com)